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Year : 2016  |  Volume : 2  |  Issue : 2  |  Page : 102-104

Sorafenib-induced pemphigus vulgaris

Department of Dermatology, Maharashtra Medical Foundation, Joshi Hospital, Pune, Maharashtra, India

Correspondence Address:
Ajay Deshpande
Maharashtra Medical Foundation, Joshi Hospital, 777, Shivaji Nagar, Pune - 411 004, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2455-3972.196172

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Sorafenib is a tyrosine kinase inhibitor approved for the treatment of primary kidney cancer, advanced primary hepatocellular carcinoma and radioactive iodine-resistant advanced thyroid carcinoma. Sorafenib is known to cause milder cutaneous side effects such as maculopapular rash and serious cutaneous drug reactions such as desquamation of the skin, hand-foot syndrome Stevens-Johnsons syndrome and toxic epidermal necrolysis. We report a histopathologicaly proved case of pemphigus vulgaris caused by sorafenib.

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