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Year : 2017  |  Volume : 3  |  Issue : 2  |  Page : 81-83

Intralesional tranexamic acid: Safe and effective way of treatment for melasma

1 Chief Dermatology Consultant & Managing Director, Cleo Laser & Skin Clinic, Hyderabad, Telangana, India
2 Department of Dermatology, M.N.R Medical College, Sangareddy, Telangana, India

Correspondence Address:
Dr. Vani Veggalam
Cleo Skin Clinic, Door No: G6, Manjeera Majestic, Jntu Hitech City Road, KPHB Colony, Hyderabad, Telangana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijdd.ijdd_24_17

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Many studies suggested the use of tranexamic acid (TA) as a treatment modality for melasma, however, there are many limitations in the use of oral and intravenous dosage forms of TA because of adverse effects and contraindications resulted by its thrombolytic property. Topical application of TA is not effective because of its poor penetration through epidermis. Intradermal injections into the localized lesions of melasma regions or intralesional administration of TA were reported to be effective way of treatment for melasma with minimum risk of adverse effects. We report a case of a 40-year-old woman, who was treated with a minimum effective dilution of intradermal TA at localized hyperpigmented regions. The results were noted and analyzed with photographs taken during the treatment and by considering the patient satisfaction scores. The patient showed good improvement at the end of 4 weeks.

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