CASE REPORT |
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Year : 2019 | Volume
: 5
| Issue : 2 | Page : 107-109 |
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D-penicillamine-induced elastosis perforans serpiginosa in a case of Wilson's disease
Shefali Saini1, Vidya D Kharkar1, Aabha Nagral2
1 Department of Dermatology, Venereology and Leprosy, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India 2 Department of Gastroenterology, Jaslok Hospital, Mumbai, Maharashtra, India
Correspondence Address:
Dr. Shefali Saini Room No. 905, UG/PG Hostel, Seth G.S. Medical College and KEM Hospital, Parel, Mumbai - 400 012, Maharashtra India
Source of Support: None, Conflict of Interest: None | Check |
DOI: 10.4103/ijdd.ijdd_53_19
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The use of D-penicillamine has been well established in various disorders, mainly Wilson's disease, cystinuria, and rheumatoid arthritis. Elastosis perforans serpiginosa (EPS) is a rare perforating dermatosis, occurring as an uncommon sequel of long-term high-dose D-penicillamine therapy. We present a rare case of EPS in a known case of Wilson's Disease on D-penicillamine therapy. Biopsy revealed characteristic “lumpy-bumpy” elastic fibers, a finding specific to penicillamine-induced EPS.
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