Bilastine up-dosing in chronic urticaria: A review

Kiran Godse; Murlidhar Rajagopalan; Bela Shah; Mukesh Girdhar; Kupra Shankar; Vijay Zawar; Abhishek De; Nidhi Sharma; Sushil Tahiliani; Anant Patil

doi:10.4103/ijdd.ijdd_30_21

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Year : 2022 | Volume : 8 | Issue : 2 | Page : 55-58

Bilastine up-dosing in chronic urticaria: A review

Kiran Godse¹, Murlidhar Rajagopalan², Bela Shah³, Mukesh Girdhar⁴, Kupra Shankar⁵, Vijay Zawar⁶, Abhishek De⁷, Nidhi Sharma⁸, Sushil Tahiliani⁹, Anant Patil¹⁰
¹ Department of Dermatology, Dr. DY Patil Medical College, Nerul, Navi Mumbai Maharashtra, India
² Department of Dermatology, Apollo Hospital, Chennai, India
³ Department of Dermatology, BJ Medical College, Ahmedabad, Gujarat, India
⁴ Department of Dermatology, Max Super Speciality Hospital, New Delhi, India
⁵ Department of Dermatology, Krupa Shankar Skin Care Center, Mallige Hospital, Bengaluru, Karnataka, India
⁶ Department of Dermatology, Skin Diseases Center, Nashik, India
⁷ Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal, India
⁸ Department of Dermatology, The Medicity, Medanta Hospital, Gurugram, Haryana, India
⁹ Department of Dermatology, Hinduja Hospital, Mumbai, India
¹⁰ Department of Pharmacology, Dr. DY Patil Medical College, Nerul, Navi Mumbai, Maharashtra, India

Correspondence Address:
Kiran Godse
Department of Dermatology, Dr. DY Patil Medical College, Nerul, Navi Mumbai Maharashtra
India

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/ijdd.ijdd_30_21

Chronic urticaria, a heterogenous skin condition can be difficult to treat in many patients. It can adversely affect patient’s quality of life. Bilastine is a useful armamentarium for the management of chronic urticaria. This second generation H1 antihistamine is distinguished from most of its counterparts. Non-sedating potential, fast onset and longer duration of action, less risk of drug interactions and once daily administration make it an attractive option for use. In patients with chronic urticaria, not showing satisfactory response to standard doses, its dose can be increased up to four fold. In this review, we discuss the evidence of higher dose of bilastine in chronic urticaria and its place in therapy.

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