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Year : 2022  |  Volume : 8  |  Issue : 2  |  Page : 89-93

Recalcitrant livedoid vasculopathy: A successful treatment with oral rivaroxaban

Department of Dermatology, KJ Somaiya Medical College, Mumbai, Maharashtra, India

Correspondence Address:
Hari Shivaram Pathave
Department of Dermatology, KJ Somaiya Medical College, Mumbai 400022, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijdd.ijdd_25_21

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Livedoid vasculopathy (LV) is a chronic prothrombotic disease of cutaneous microcirculation resulting in cutaneous ischemia and infarction. Chronic disease often results in painful ulcerations and atrophie blanche on the lower extremities, predisposing affected patients toward infection and high morbidity. Treatment of LV is often difficult and prolonged. Owing to the postulated pathophysiology of vasculopathy, rivaroxaban has been recently suggested as a treatment modality and seems to induce significant improvement in some patients. Compared with other treatments such as classic anticoagulants or intravenous immunoglobulin, rivaroxaban is far more convenient as it does not require injection, international normalized ratio monitoring or hospitalization. Herein, we report the successful treatment of recalcitrant LV in two Indian patients with oral rivaroxaban along with a review on use of rivaroxaban in LV.

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