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CASE REPORT
Year : 2023  |  Volume : 9  |  Issue : 1  |  Page : 34-35

Nicolau syndrome: A dreaded complication of vitamin-12 injection


1 Mahatma Gandhi Institute of Medical Sciences, Sewagram, India
2 Department of Dermatology, Venereology & Leprosy, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha, Maharashtra, India

Correspondence Address:
Sonia P Jain
Department of Dermatology, Venereology & Leprosy, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha 442102, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijdd.ijdd_21_23

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Nicolau syndrome, often referred to as embolia cutis medicamentosa or livedoid dermatitis, is an uncommon cutaneous adverse drug reaction that develops at the site of injection of some specific pharmaceuticals. Commonly seen with NSAIDS given intra-muscularly, it can be observed with a variety of drugs given subcutaneously, intra-articularly and sometimes intravenously. Here, we present a rare case of Nicolau syndrome following an intramuscular injection of Vitamin B-12 over gluteal region that turned out to be fatal.


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