Indian Journal of Drugs in Dermatology

CASE REPORT
Year
: 2018  |  Volume : 4  |  Issue : 1  |  Page : 23--25

Efficacy of doxycycline monotherapy in treating rhinoscleroma


Mithali Jage1, Kinjal Deepak Rambhia2, Uday S Khopkar2 
1 Department of Dermatology, Venereology and Leprosy, Seth G. S. Medical College, KEM Hospital, Mumbai, Maharashtra, India
2 Department of Dermatology, Seth G. S. Medical College, KEM Hospital, Mumbai, Maharashtra, India

Correspondence Address:
Dr. Kinjal Deepak Rambhia
B-105 Kalpataru Classic, Chincholibunder Road, Malad West, Mumbai - 400 064, Maharashtra
India

Rhinoscleroma, also known as Mikulicz disease, is a chronic granulomatous infection of the nasopharyngeal nucosa causing disfigurement and debilitation. A 27-year-old male presented with nasal mass and obstruction. Histopathology revealed dense, diffuse, mixed inflammatory infiltrate consisting of neutrophils, lymphocytes, plasma cells, and foamy macrophages. Mikulicz cells which are foamy macrophages containing filamentous, granular, and fragmented bacilli were seen. The patient was diagnosed as rhinoscleroma and was started on capsule doxycycline 100 mg twice daily. After 6 weeks, marked improvement in the lesions and symptoms was noticed.


How to cite this article:
Jage M, Rambhia KD, Khopkar US. Efficacy of doxycycline monotherapy in treating rhinoscleroma.Indian J Drugs Dermatol 2018;4:23-25


How to cite this URL:
Jage M, Rambhia KD, Khopkar US. Efficacy of doxycycline monotherapy in treating rhinoscleroma. Indian J Drugs Dermatol [serial online] 2018 [cited 2022 Jun 26 ];4:23-25
Available from: https://www.ijdd.in/article.asp?issn=2455-3972;year=2018;volume=4;issue=1;spage=23;epage=25;aulast=Jage;type=0